C-REACTIVE PROTEINS AND ESR LEVELS IN PATIENTS WITH AND WITHOUT APICAL PERIODONTITIS. A CROSS-SECTIONAL STUDY

Authors

  • Mohammad Iqbal Department of Biochemistry, Khyber College of Dentistry, Peshawar.
  • Shakeel Anwar Department of Preventive and Community Dentistry, Khyber College of Dentistry, Peshawar.
  • Roshan Ali Department of Biochemistry, Khyber Medical University, Peshawar.
  • Zahoor Ahmad khan Department of Biochemistry, Khyber Medical College, Peshawar.
  • Niaz Ali Department of Biochemistry, Khyber Medical College, Peshawar.
  • Robina Nazli Department of Biochemistry, Khyber Medical College, Peshawar.

DOI:

https://doi.org/10.33279/jkcd.v8i3.551

Keywords:

Apical periodontitis, inflammatory markers, C-reactive proteins, Erythrocyte Sedimentation Rate.

Abstract

Objectives:This research aimed to determine the relative levels of serum C-reactive Proteins (CRP )and Erythrocyte Sedimentation Rate ( ESR) and compare them in patients with and without apical periodontitis by using Mann-Whitney U test and Spear man correlation coefficient between CRP level, ESR and CAL values.
Materials & Methods:This analytical, cross-sectional study was conducted at Khyber College of Dentistry Peshawar with a sample of 150 subjects. Data were analyzed using SPSS version 20. And Significance level was (P<0.05).
Results:The mean CRP level in patients with apical periodontitis was higher than healthy control, but this was statistically insignificant (P>0.05). Similarly, the mean ESR level in patients with apical periodontitis was higher than healthy control, but this was statistically insignificant (P>0.05).
Conclusion: In subjects free from the systemic disease the CPR and ESR level does not differ among apical periodontitis versus non-periodontitis. This means the apical periodontitis in systemically healthy individuals remains localized and do not produce systemic inflammation.

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Published

2018-09-30

How to Cite

Iqbal, M. ., Shakeel Anwar, Roshan Ali, Zahoor Ahmad khan, Niaz Ali, & Robina Nazli. (2018). C-REACTIVE PROTEINS AND ESR LEVELS IN PATIENTS WITH AND WITHOUT APICAL PERIODONTITIS. A CROSS-SECTIONAL STUDY. JOURNAL OF KHYBER COLLEGE OF DENTISTRY, 8(3), 20–24. https://doi.org/10.33279/jkcd.v8i3.551