FREQUENCY OF METASTATIC SQUAMOUS CELL CARCINOMA IN CERVICAL LYMPH NODES IN PATIENTS PRESENTING WITH ORAL SQUAMOUS CELL CARCINOMA
DOI:
https://doi.org/10.33279/jkcd.v8i02.427Keywords:
Fine needle aspiration cytology, lymph nodes, squamous cell carcinoma, reactive hyperplasiaAbstract
Objective: To determine the frequency of FNAC (Fine needle aspiration cytology) findings in cervical lymph nodes of patients presenting with squamous cell carcinoma of the oral cavity in our setup.
Materials & Methods: This Cross-sectional descriptive study was done in Advanced FNAC clinic, Peshawar, from January 2017 to March 2018 (1 year, three months). Non-probability purposive sampling was done. A total of 54 diagnosed cases of oral squamous cell carcinoma presenting with cervical lymphadenopathy were included in the study. Patients in whom lymphadenopathy was due to infection and tuberculosis were excluded from the study. FNAC samples were obtained from the cervical lymph nodes of patients; slides were prepared and examined. The results were drawn accordingly. Mean, and the standard deviation was calculated for quantitative variables, e.g. age. Frequencies and percentages were calculated for qualitative variables like diagnosis and gender. Data were analyzed using SPSS -18.
Results: A total of 54 cases diagnosed as Squamous cell carcinoma of the oral cavity in Khyber college of dentistry were referred for cervical lymph node FNAC. Age of study sample ranged from 40 to 60 years, with a mean of 54 ±12 SD. There were 49 (90%) male and 5 (10%) female cases. Cervical lymph node FNAC findings showed that about 14 (26%) cases had a large number of immunoblasts with no atypical cells, suggestive of reactive lymphoid hyperplasia. While 40 (74%) cases had dimorphic squamoid cells with hyperchromatic nuclei and high nuclear to cytoplasmic ratio with lymphoid aggregates, suggestive of metastatic squamous cell carcinoma.
Conclusion: This study showed that the frequency of metastatic squamous cell carcinoma in cervical lymph nodes was very high in patients with squamous cell carcinoma of the oral cavity as compared to reactive hyperplasia. FNAC is diagnostically important and minimally invasive technique that can be used in the workup of patients presenting with cervical lymphadenopathy.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2018 Muhammad Waqas, Sultan Zeb Khan, Ghulam Rasool
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes .
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
