RESPONSE TO SYMPTOMATIC TREATMENT IN MITRAL VALVE PROLAPSE, AN EXPERIENCE AT KHYBER PAKHTOONKHWA
DOI:
https://doi.org/10.33279/jkcd.v13i1.102Keywords:
Mitral valve prolapse (MVP), Mitral regurgitation(MR)Abstract
Objectives: To determine the subjective response to treatment in mitral valve prolapse patients.
Materials and Methods: This was a cross-sectional observational study was conducted in department of Cardiology LRH Peshawar, from 21 November 2019 to 30 April 2020. All consecutive patients having Prolapse of mitral valve fulfi lling the inclusion criteria were studied. Their subjective response to treatment were studied. Statistical Analysis was done with SPSS version 18.0 software. Percentages & Frequency were used for categorical variables like ender, mitral regurgitation and response to treatment. While mean and standard deviation was used for quantitative variables like age were calculated.
Results: A total No of 142 patients have documented evidence of echocardiographic mitral valve prolapse were included. They all were and treated with Beta blockers and selective serotonin reuptake inhibitors (SSRI). Mean age were 19.45±7.32 years. Females were 89(62.7%). Out of total study population 128(90%) have palpitation, 111(78%) have chest pain, 102(72%) have dizziness, 93(65%) have Apprehension & Pre-syncope in 85(60%). Of the total, 32(22.53%) patients were also taking ACI/ARB and 42(29.5%) were on benzodiazepine. Their 04 month’s subjective response to treatment was documented. Of all the patients 16 patients have lost to follow up. In the remaining 126 patients, response to medications were excellent in 21(16.67%), good in 29(23.01%), satisfactory/Fair in 41(32.53%). No response to symptoms was documented in 23(18.25%) patients and 12(9.5%) have worsening of symptoms.
Conclusion: Symptomatic patients have echocardiographic documented prolapse of Mitral valve fairly respond to SSRIs and beta blockers.
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Copyright (c) 2023 Imran Khan, Shah Zeb, Hidayatullah, Muhammad Ishaq khan , Muhammad Waleed, Muhammad Salman

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